| Class | Departure Station | Arrival Station | Departure | Arrival | Travel time |
|---|---|---|---|---|---|
| Semi Sleeper | Asuncion Bus Station | Caacupe | 06:30 | 08:40 | 2h 10m |
| Semi Sleeper | Asuncion Bus Station | Itaugua | 06:30 | 08:10 | 1h 40m |
| Semi Sleeper | Mariano Roque Alonso Agencia | Barrio San Pedro | 05:35 | 08:30 | 2h 55m |
| Semi Sleeper | Mariano Roque Alonso Agencia | Barrio San Pedro | 08:40 | 11:05 | 2h 25m |
| Semi Sleeper | Mariano Roque Alonso Agencia | Barrio San Pedro | 11:20 | 14:20 | 3h 0m |
| Semi Sleeper | Mariano Roque Alonso Agencia | Barrio San Pedro | 21:30 | 00:25 | 2h 55m |
| Semi Sleeper | Parada Luque | Barrio San Pedro | 05:25 | 08:30 | 3h 5m |
| Semi Sleeper | Parada Luque | Barrio San Pedro | 08:20 | 11:05 | 2h 45m |
| Semi Sleeper | Parada Luque | Barrio San Pedro | 10:55 | 14:20 | 3h 25m |
| Semi Sleeper | Parada Luque | Barrio San Pedro | 21:20 | 00:25 | 3h 5m |
| Semi Sleeper | Terminal de Arroyos y Esteros | Barrio San Pedro | 06:40 | 08:30 | 1h 50m |
| Semi Sleeper | Terminal de Arroyos y Esteros | Barrio San Pedro | 09:30 | 11:05 | 1h 35m |
| Semi Sleeper | Terminal de Arroyos y Esteros | Barrio San Pedro | 12:20 | 14:20 | 2h 0m |
| Semi Sleeper | Terminal de Arroyos y Esteros | Barrio San Pedro | 22:25 | 00:25 | 2h 0m |