Bus
Travelling from Medellin to Santiago Chile overland will inevitably take longer but in many cases it is
the cheapest option if you opt for a bus.
Things to remember: For a more comfortable ride opt for a higher-class bus wherever possible. These buses usually have soft reclining seats and are equipped with air-conditioning and on-board toilets.
They often include water, snacks or a light lunch into your ticket price and make bathroom stops en-route.
Companies operating bus routes between Medellin and Santiago Chile
Atlas Cumbres, Buses Linatal, Nar Bus, Pullman Bus, Pullman del Sur
Van
Vans are a great alternative - or, in many cases - your only option - if you need to travel overland within one and the same province or neighbouring provinces or states. Vans ply the roads between Medellin and Santiago Chile, too.
Things to remember: When travelling by van with huge luggage buying a separate seat for your suitcase or backpack is a good idea. Do not expect there is a roomy luggage compartment in a van - there is actually none and your fellow passengers are unlikely to appreciate your luggage stuck under their feet, alas.
Companies operating vans between Medellin and Santiago Chile
Chirak, Partner Reps Chile